Reply To: Exception of type ‘Ansys.Fluent.Cortex.CortexNotAvailableException’ was thrown.

[tsiriaks]

Change your GPGPU to 0 unless you have a really good graphics card.

There should be a shortcut for Fluent created on your Windows startup (similar to how you launch Workbench). If you don't see one, just open CMD Prompt and enter the following command

"%awp_root195%fluentntbinwin64fluent.exe"

If you have the same issue for stand-alone Fluent, in the Fluent Launcher -> More options -> Environment, then add the following in there

FLUENT_LAUNCHER_OPTIONS=-driver msw

If that still doesn't help, try changing the 'msw' to 'opengl' or 'opengl2'