One suggestion is to rename the directory:Â %APPDATA%\Ansys\v242 to v242.old Try to run after that. If this doesn't help... Is there a reason that installation is to: D:\Ansys\Ansys Inc? I would try uninstalling and renaming the d:\Ansys\Ansys Inc directory to Ansys.old Then reinstall making sure to right-click on setup.exe and choosing: "run as administrator" Also, try default installation to c:\program files\Ansys Inc.
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