As discussed earlier, monitor the convergence of coupling participants and decide the number of Fluent iteration to be used per coupling iteration (here the goal is to converge the fluent at the end of coupling step and not every coupling iteration) to optimize the solve time or use machine with higher processes and memory.
I recommend that you build up to the final two-way analysis incrementally, progressively adding complexity with each step. You can find the recommended steps for building any coupled analysis here: Building Up to a Coupled Analysis (ansys.com)
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